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Review of cost-effectiveness

Researchers from Duke University compared clinically proven, nonsurgical weight-loss treatments for people who are overweight and obese, including meal replacement programs (Jenny Craig), lifestyle programs (Vtrim and WW), and medications (Qsymia, Lorcaserin, Orlistat). Their 2014 meta-analysis, published in Obesity, reported the finding that WW is the most cost-effective. 

  Cost ($) Mean
(95% CI)
Effectiveness
Mean
(95% CI)
ACER ($) Mean
(95% CI)
WW 377 (291 - 471) 2.4 (1.8 - 3.0) 155 (110 - 218)
Vtrim 682 (521 - 854) 3.2 (1.4 - 4.9) 213 (127 - 493)
Qsymia 7.5/46 1,366 (1,036 - 1,674) 6.7 (4.7 - 8.6) 204 (134 - 317)
Orlistat 3 x 120 mg 1,518 (1,149 - 1,895) 2.8 (2.4 - 3.2) 546 (390 - 736)
Lorcaserin 2 x 10 mg 1,743 (1,311 - 2,165) 3.2 (2.6 - 3.8) 545 (399 - 725)
Jenny Craig average income 3,152 (2,378 - 3,943) 7.4 (5.7 - 8.9) 424 (302 - 594)
Jenny Craig high income 2,512 (1,931 - 3,124) 7.4 (5.7 - 8.9) 338 (248 - 476)


​Source: Finkelstein EA, Kruger E. Meta- and Cost-Effectiveness Analysis of Commercial Weight Loss Strategies. Obesity. 2014;22:1942-1951.

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