Bupropion-Naltrexeon
Bupropion-Naltrexone Prescription Online
Available
Lose up to 7% of your body weight on average*
Convenient oral medications — no injections required
Dual-action support for appetite and cravings, empowering you to build healthier habits that last
Cost included with WeightWatchers Clinic membership
Prescriptions require online consultation with a healthcare provider who will determine if a prescription is appropriate.
*Eligible patients lost an average of 6% of their body weight in a 56-week clinical trial evaluating 32 mg naltrexone combined with 360 mg bupropion daily, paired with diet and exercise.
All medical services are provided through our affiliated medical group, WeightWatchers Clinic.
Important safety information for Bupropion XL
Important safety information for Naltrexone HCI
What is bupropion-naltrexone?
Bupropion and naltrexone are two medications that can be prescribed in combination to help you lose weight or maintain weight loss. Bupropion is commonly prescribed as an antidepressant and helps reduce appetite and cravings, while naltrexone — used to treat certain addictions — helps manage emotional or reward-driven eating behaviors. Together, these medications support weight loss by addressing both the biological and emotional factors behind overeating.
Important safety information for Bupropion XL ↗
Important safety information for Naltrexone HCI ↗
How does bupropion-naltrexone work?
When taken together, bupropion and naltrexone target the brain’s appetite and reward systems to control hunger, reduce cravings, and help you eat less overall. Bupropion helps regulate the areas of the brain responsible for hunger cues, making it easier to control portions and food intake. Naltrexone works by blocking certain reward pathways, reducing the pleasure derived from eating comfort foods. This combined approach makes it easier to build and maintain healthier eating habits.
Is bupropion-naltrexone covered by insurance?
The cost of the medication is included as part of the WeightWatchers Clinic membership, making it a great option for people whose insurance does not cover the cost of other weight-management medications.
weight loss*
Bupropion and naltrexone work together to target the brain’s appetite and reward systems to help you feel less hungry and reduce your cravings. This can help individuals eat less, leading to an average weight loss of 6% when combined with diet and exercise.
*Eligible patients lost an average of 6% of their body weight in a 56-week clinical trial evaluating 32 mg naltrexone combined with 360 mg bupropion daily, paired with diet and exercise.
After 1 year, WW Clinic members prescribed weight management medications who added the WW Points program lost 8% more weight than WW Clinic members who did not.**
**Based on observational study of 1400 Clinic members who added the WW Points program to their membership and lost -17.7% body weight on average, compared to 2606 Clinic members who did not start a WW membership during this timeframe and lost -16.4% body weight on average.
The power of pairing weight-loss meds
with WW Points Program
Science shows that weight-loss medications should be combined with lifestyle changes. Weight Watchers makes that easier.
Cost and comparisons
All the details on bupropion-naltrexone’s price and how it stacks up against other weight-loss medications.
Cost included with WW Clinic membership
WeightWatchers Clinic membership required
Membership starts at $74/month.
Getting started takes just a few steps.
Tell us about your medical history and weight journey to see if you medically qualify for medications.
After you join WW Clinic, your dedicated medical provider will review your assessment and, if eligible, develop your treatment plan.
Your provider will consider appropriate medications for you, which in many cases include GLP-1s.
Start the program in the WW app, meet with your Registered Dietitian, and join the Clinic community on Connect.
More about weight-loss
medications
The WW guide to weight-loss medications
Weight loss medication side effects — and how to manage them
Lifestyle changes everyone on a prescription weight-loss med should make
The WW guide to weight-loss medications
Weight loss medication side effects — and how to manage them